Dr Susan Little 11.10.11

Dr Susan Little 11.10.11 - Controlling HIV Fact or Fiction...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
11/9/11 1 Susan Little, M.D. Professor of Medicine University of California San Diego Controlling HIV: Fact or Fiction? 11/10/11 1 Financial Disclosures: None HIV Transmission: It’s all about sex! l See, the problem is that God gives men a brain and a penis, and only enough blood to run one at a time. z ~ Robin Williams “Sex without love is an empty experience, but as empty experiences go it's one of the best.” ~Woody Allen 2 11/10/11 The Sexual Network (1): ! B & C are MSM involved in a monogamous relationship for 6 months ! 3 months into above relationship, B started another relationship with A ! B developed fever/chills – returned to C and continued his l monogamous z relationship with C ! B subsequently partnered with D 3 11/10/11 B C A D B then presented to the SD PHD with a sore throat and was treated for gonorrhea
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
11/9/11 2 The Sexual Network (2): ! B found to be HIV positive – referred partner C to UCSD ! C presented to UCSD on 6/29/05 sick with acute HIV infection (HIV RNA+/HIV Ab neg). C counseled and then referred B. 4 11/10/11 B + C A D B presented to UCSD with early HIV infection on 7/1/05. B referred partners A and D. A contacted, but refused to come in for testing. D presented to UCSD on 7/5/05 and tested negative for HIV, but had positive throat Cx for gonorrhea. + The Sexual Network (3): ! Patient E then presented to UCSD with Acute HIV infection and identified patient A as his source partner. ! Patient A presented 5 months after the first patient (B) (11/18/05) at which time he claimed to have unknown HIV status and was found to have chronic HIV infection. 5 11/10/11 B + C + A D Patient A was also (subsequently) found to be the source of transmission for Patient F, who presented 9/27/05 with Acute HIV infection. + E + F + l What network theory teaches us is that connections, even within the most complex systems, are not random (that is, they are not unpredictable). Instead, networks behave in ways that we can theorize, model, and predict. z The PLoS Medicine Editors. It's the Network, Stupid : Why Everything in Medicine Is Connected. PLoS Med 2008. Transmission Dynamics
Background image of page 2
11/9/11 3 Controlling HIV: Outline ! The Rationale ! The Reality ! The Future 11/10/11 7 11/10/11 Total: 33.4 million (31.1 – 35.8 million) Western & Central Europe 850 000 [710 000 – 970 000] Middle East & North Africa 310 000 [250 000 – 380 000] Sub-Saharan Africa 22.4 million [20.8 – 24.1 mil ion] Eastern Europe & Central Asia 1.5 million [1.4 – 1.7 mil ion] South & South-East Asia 3.8 million [3.4 – 4.3 mil ion] Oceania 59 000 [51 000 – 68 000] North America 1.4 million [1.2 – 1.6 mil ion] Latin America 2.0 million [1.8 – 2.2 mil ion] East Asia 850 000 [700 000 – 1.0 mil ion] Caribbean 240 000 [220 000 – 260 000] Adults and children estimated to be living with HIV, 2008 8 Prevention is the Foundation for Treatment Sustainability ! 1,200,000 people were started on ART in 2009 ! 2,600,000 new infections occurred that same year !
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 18

Dr Susan Little 11.10.11 - Controlling HIV Fact or Fiction...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online