Lecture 4 - sequence of nucleotides (with “user info”)...

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Nucleic Acids (4) 1
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You should be able to… n Name the monomer n Draw a monomer n Name and correctly place the “external” bonds n Explain the significance of the types discussed in class n Summarize protein synthesis 2
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Nucleic Acids n Nucleotide n Sugar + Phosphate + Base n Nitrogenous base n Pentose sugar n A, T, G, C n Phosophodiester bond 3
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Pyrimidines and  Purines n Cytosine n Uracil n Thymine 4 C U T
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“external” bonds 5 What kind of bond is this?
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RNA 6
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Becoming double-stranded:  complementary base pairing Why is DNA  the genetic  material for  multicellular  organisms  and not  RNA? 7
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Secondary Structure of  DNA 8
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DNA Synthesis 9 Semi-conservative  replication: half-old/half- new Complementary base  pairing + enzymes+ energy
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What is a gene? n The 
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Unformatted text preview: sequence of nucleotides (with “user info”) that code for a polypeptide 10 Comparing the structures of DNA and RNA 11 RNA Secondary Structure 12 RNA World n Simpler to assemble n Self replicating n Template via base-pairing n Ribozymes catalyze reactions n Peptide bond formation by ribosomes! 13 Other Important Types Genetic material DNA, RNA Energy transfer Nicotinamide Adenine Dinucleotide (NAD+/NADH) Adenosine TriPhosphate (ATP) and ADP 14 NADH ATP Functions of Nucleic Acids: Energy Transfer 15 • ATP-ADP-AMP • NADH/NAD+ • And others Why is ATP able to store energy? How does NADH transfer energy?...
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This note was uploaded on 02/27/2012 for the course BIO 0150 taught by Professor Roberts during the Fall '09 term at Pittsburgh.

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Lecture 4 - sequence of nucleotides (with “user info”)...

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