bio- chap 43

bio- chap 43 - I. NonSpecific Defenses Afainst Infection A....

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I. NonSpecific Defenses Afainst Infection A. 1 st Line of Defense -Skin and Mucous Membranes, and Secretions B. 2 nd Line of Defense: does not distinguish among pathogens 1. Phagocytic Cells (monocytes and neutrophils) a. antigens that penetrate first line of def. b. Phoagcytosis: ingestion of invading orgs. By certain types of WBCs c. Monocytes eventaully develop into macrophages d. Eosinophils- against larger parasitic invaders e. NK cells- non sepcific destory virus infected body cells. Cause a cell’s memb to burst instead of phagocytic action 2. Inflammatory Response a. increased flow of local blood supply causing fluid leaks into nearby tissues causing swelling b. initiated by chemical signals either from pathogen or body itself - histamine produced by basophils and mast cells from connective tissue - prostaglandins from leukocytes that promote blood flow to place of injury c. enhanced flow of phagocytes to injured area d. phagocytosis mediated by chemokines- checmo tactic factors e. neutrophils 1 st , then monocytes=> macrohages f. pus is dead cells and antigens
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This note was uploaded on 02/25/2012 for the course BIO 1421 taught by Professor Farr during the Fall '08 term at Texas State.

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bio- chap 43 - I. NonSpecific Defenses Afainst Infection A....

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