Bio Notes-Cancer-1

Bio Notes-Cancer-1 - Cancer Normal Cells -With few...

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Cancer Normal Cells -With few exceptions, cells within a tissue adhere to one another and are joined by various junctions. -Chemical signals between cells tell them whether they should be dividing or not dividing. -Stimulatory growth factors. -Inhibitory growth factors. Regulation of Cell Division -Two sets of genes control cell division. -Proto-oncogenes (regulate cell growth) - Tumor suppressor genes (keep the cells from getting out of hand) Normal Cell Characteristics -Genetically stable. -Differentiate and adhere to other cells. -Respond appropriately to growth signals. -Undergo a limited number of cell cycles. Cancer Cell Characteristics -Genetically unstable. -Not differentiated- Do not adhere to other cells. -Insensitive to inhibitory growth signals. -Unlimited number of cell cycles. -Invade and metastasize. Cancer Cells -Carcinogenesis -Development of cancer. -Cancer is a genetic disease requiring at least ten mutations, each propelling cells toward tumor development. *Each tumor is composed of cells that are experiencing uncontrolled growth.
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Bio Notes-Cancer-1 - Cancer Normal Cells -With few...

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