bio- telomeres

bio- telomeres - conflicts that require the presence of a...

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Telomeres What are telomeres? What role do they play? Telomeres only have a role to play in the structure of eukaryotic DNA. Prokaryotic DNA exists in a circular configuration and therefore, has no “ends” to deal with. That particular problem arises in the linear arrangement of the bases in eukaryotic DNA. Telomeres are multiple repetitions of short nucleotide sequences, not genes. The general replication in a telomere differs between approximately 100 and 1000. The typical sequence for the repetition of nucleotide sequence in the human is TTAGGG. The mechanisms of replication of DNA in the eukaryote cell propose some
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Unformatted text preview: conflicts that require the presence of a telomere to solve certain problems. DNA polymerase only allows nucleotides to be added to the 3’ end of a pre-existing polynucleotide, and therefore, the 5’ ends cannot be completed. Consequently, replication causes strands to become shorter and shorter. This continuous shortening would result in the deletion of indispensable genes in the DNA sequence. Telomeres, on the other hand, preserve an organism’s genes from removal during replication. Telomeres, working with other special proteins, inhibit the cell’s systems from detecting and supervising DNA damage....
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