Question: Outline the advantages of using Selective Seretonin Reuptake Inhibitors (SSRI’s) compared to tricyclic antidepressants. Your answer should include at least one example of each drug and its recommended daily dose.Selective serotonin reuptake inhibitors (SSRIs) are considered to have fewer antimuscarinic side-effects (such as dry mouth, blurred vision) then tricyclic antidepressants (from which class amitriptyline hydrochloride belongs). Since dry mouth and blurred vision effects were bothering Mrs Adam, a SSRI might be a more suitable antidepressant for her. Although fluoxetine is the most common SSRI, paroxetine is considered (at least by some people) to cause even less effects such as dry mouth and blurred vision then other SSRIs. Generally, all antidepressants may cause such side-effects, but some (like SSRIs, from which class fluoxetine and paroxetine are the commonest) may have slightly less of those side-effects while others have more. Nausea and insomnia are the most common side effects of SSRI, but these effects may also be caused by other antidepressants.
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