Using SNPs to inform us about Disease Susceptibility

Using SNPs to inform us about Disease Susceptibility -...

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Using SNPs to inform us about Disease Susceptibility Introduction What are SNPs? SNPs, single nucleotide polymorphisms, are small genetic changes or variations which can occur within the DNA sequence of an individual (1). Usually, for a variation to be considered as a SNP, it must occur in at least 1% of a population. Even if 99% of the DNA sequences in human beings are similar across a population, alterations in the DNA sequence can have a profound influence on the response of individuals to disease, bacteria, viruses and other chemicals and drugs (2). The vast number of phenotypic
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Unformatted text preview: variations namely cancer, diabetes, cardiovascular disease, obesity are likely to be encoded in the wide spectrum of variation in genes which are primarily SNPs (3). Hence, SNPs are of great importance for biomedical research as well as development of pharmaceutical products. Moreover, scientists believe that SNP maps will undoubtedly help them to identify multiple genes associated with a myriad of complicated diseases such as cancer, diabetes and vascular diseases....
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This note was uploaded on 02/25/2012 for the course BIO 1421 taught by Professor Farr during the Fall '08 term at Texas State.

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