Important Chemokines

Important Chemokines - c. Cause b cells to procude IgG...

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Important Chemokines you should know 1. IL-8 a. Released by macrophages and neutrophils b. Acts as a cehmoattract across epithelium for other polymorphs 2. TNF a. Released by macrophages and neutrophils b. Acts as a vasodilator and increases permeability across membrane c. Stimulates neutrophil activation d. Cause endothelium to express selectin 3. IL-2 a. Released by helper th2 cells b. Helps activate b cells to stimulate activation c. Released by th1 to stimulate t cell proliferation d. Growth factor for th1 response 4. IL-12 a. Released by Th1 cell b. Used to regulate amount of Th2 cells c. Released by macros and mast cells d. Lead to ifn production in th1 cells to increase macrophage activation 5. IFN-y a. Released by Th1 cell b. Used to regulate amount of Th2 cells
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Unformatted text preview: c. Cause b cells to procude IgG antibodies instead of IgM d. Activates macrophages 6. IL-4 a. Released by Th2 cells b. Used to regulate amount of Th1 cells c. Stimulate b cell to produce IgE d. Suppresses macrophage activation e. Growth factor for th2 response 7. IL-10 a. Released by Th2 cells b. Used to regulate amount of Th1 cells c. Stimulate b cell maturation d. Suppresses macrophage activation e. Released by b ten cells to regulate th1 inflammatory response 8. Il-5 a. Released by Th2 cells b. activate eosiophils 9. IL-1 a. Released by mast cells and macrophages b. Increase vascular permeability c. Cause endothelium to express selectin...
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This note was uploaded on 02/25/2012 for the course ECO 101 taught by Professor Staff during the Fall '10 term at Texas State.

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