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exam 1 notes - 1/8 Tuberculosis Blastomyces Coccidioides...

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1/8 19:52 T-uberculosis B-lastomyces C-occidioides H-istoplasma These are fungi with certain affinities for different areas.  Can lay dormant, form  granulomas. BCH are the dimorphic fungi that cause disease in humans. Basophils has more granules Histamines in granules Like to recruit eosinophils Respond to parasitic worms (endoparasites, being roundworms etc. or leishmania) Monocytes have indented nucleus. cortisol/Cortisone are steroids and anti-inflammatory
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12/13 19:52 Intro to Medical Mycology Study of Fungi, yeasts, molds Fungi is colloquial term for mycota kingdom Molds are filamentous, cellular, nucleated fungi Yeasts are not filamentous, they are eukaryotic, and bud asymmetrically. Yeasts are unicellular budding organisms Molds ~ fungi Multicellular filamentous organisms forming hyphae Ex. Mildew Chemoheterotrophs Require organic molecules as nutritional source of energy and carbon Most are aerobic or facultatively anaerobic Very few are anaerobic Most are saprophytic in soil and water (can live on dead animals and plants.) Kingtom Mycota are fungi. Protista Protozoa Algae Prototheca The only pathogenic algae Can kill it or damage it with anti-membrane drugs Amphotericin
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12/13 19:52 Drug that damages cell membranes Can’t use this on humans since we have cell membranes. Over 100k species of fungus Approx. 100 (maybe 200) pathogenic for humans Eukaryotic organisms Fungi often identified on physical appearance of colony and microscopic appearance of  spores Vegetative: Cells with catabolism and growth Spores can be asexual or sexual Cell membranes Contain sterols in islands or clumps Phospholipid bilayer Cell walls Contain glucans, mannans, chitin (poly-N-acetylglycosamine) (no peptidoglycan) Nutritional Adaptations of Fungi Often grow where bacteria don’t Prefer pH 5.0, at which most bacteria do not grow Since aerobic, often grow on surfaces Can stand high sugar or salt Can grow at low moisture Require less nitrogen than bacteria
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exam 1 notes - 1/8 Tuberculosis Blastomyces Coccidioides...

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