Gene expression 1

Gene expression 1 - Central dogma of biology: DNA DNA RNA...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Central dogma of biology : DNA DNA RNA PROTEIN Always from nucleic acid to protein, never the reverse! Ribonucleic Acid (RNA) – similar to DNA, but: - Sugar group is ribose, not deoxyribose; (ribose sugar has “OH”, deoxyribose has “H”, in position 2 of the sugar). (deoxy means faulting oxy, which is oxygen) Both RNA and DNA contain phosphate group, sugar and purine or pyrimidine base. - The base is different in DNA and RNA: DNA: ATCG RNA: UAGC A – adenine; T – thymine; C – cytocine; G – guanine; U – uracil . - So, thymine from DNA is replaced by uracil in RNA. - RNA is single stranded, DNA is double stranded; 3 TYPES OF RNA 1. mRNA (messenger RNA) – encodes for proteins; 2. rRNA (ribosomal RNA) – part of the ribosome structure; 3. tRNA (transfer RNA) – adaptor for protein synthesis. MECHANISM OF RNA SYNTHESIS (5’) CGCTATAGCGTTT (3’) DNA nontemplate (coding) strand (3’) GCGATATCGCAAA(5’) DNA template strand (can be called “opposite” to the nontemplate strand) TRANSCRIPTION (5’)CGCUAUAGCGUUU(3’) RNA transcript (it can be called “opposite” of the DNA template strand; instead of thymine, in RNA it is uracil.)
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 6

Gene expression 1 - Central dogma of biology: DNA DNA RNA...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online