Presentation93 - BacterialandViralGenetics

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Bacterial and Viral Genetics Bacteria and viruses are important disease causing organisms deserving of study.  However,  they also have advantages as experimental organisms in the study of genetics and, more  recently, they have been adapted as tools for molecular investigations. 1. They have a rapid generation time.   Two to three generations per hour.  In one day there can be as  many generations as in the human population since the time of Julius Caesar.  In three months, as  many as since the time of the Neanderthals. 2. They can be reared easily in a small space.   A test tube can easily hold more bacteria than there are  people in the world. 3. They are haploid.   Recessive mutations are not hidden in heterozygotes.  It is the equivalent of  directly examining the gametes of a eukaryote.   4. Their genomes are small.   Mapping and eventual sequencing of their genes is relatively easy since  they normally have only one small chromosome. Escherichia coli (E. coli): 4,639,221 bp, ~5000 genes Bacteriophage T4: 168,500 bp, ~300 genes
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Phenotypic/Genotypic characters utilized in bacterial genetics- Prototroph : An organism that requires only minimal media, i.e. one with the biochemical capacity to  synthesize its own amino acids, lipids, etc. from a simple sugar diet.
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This note was uploaded on 02/26/2012 for the course AGRY 320 taught by Professor Stewert during the Spring '09 term at Purdue University-West Lafayette.

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Presentation93 - BacterialandViralGenetics

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