docx (24) Final Exam essay .docx - 1 Question 1 The...

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1 Question 1 The following data were collected in a clinical trial to compare a new drug to a placebo for its effectiveness in a lowering total serum cholesterol. Generate a 95% confidence interval for the difference in mean total cholesterol levels between treatments. New Drug (n=75) Placebo (n=75) Total sample (n=150) Men (SD) Total Serum Cholesterol 185.0 (24.5) 204.3 (21.8) 194.7 (23.2) % patients with Total Cholesterol < 200 78.0% 65.0% 71.5% A. Upper limit -11.88 B. Lower limit -26.72 C. Based on the confidence interval which of the following is (are) true? (a) There is significant evidence, alpha = 0.05, to show that there is a difference in total serum cholesterol between treatments New Drug and Placebo (b) There is not significant evidence, alpha = 0.05, to show that there is a difference in total serum cholesterol between treatments New Drug and Placebo (c) The difference between total cholesterol between treatments New Drug and Placebo is essentially 0 (d) b and c.
Question 2 A study is designed to investigate whether there is a difference in response to various treatments in patients with rheumatoid arthritis. The outcome is patient’s self-reported effect of treatment. The dada are shown below. Are symptoms independent of treatment? Conduct a ChiSquare test at a 5% level of significance. Symptoms Worsened No Effect Symptoms Improved Total Treatment 1 22 14 14 50 Treatment 2 14 15 21 50 Treatment 3 9 12 29 50 4
2 Based on comparing the computed statistics to the critical value which of the following is (are) true? (a) There is significant evidence, alpha = 0.05, to show that treatment and response are not independent (b) there is not significant evidence, alpha = 0.05, to show that treatment and response are not independent (c) there is significant evidence, alpha = 0.05, to show that treatment and response are independent (d) b and c

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