lecture 10 (5) - Imipramine Photo by: Sebastian Kaulitzki...

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Imipramine Photo by: Sebastian Kaulitzki Definition Imipramine is a tricyclic antidepressant. It is sold under the brand name Tofranil in the United States. Purpose Imipramine is used to relieve symptoms of depression. Imipramine is also used in the treatment of enuresis (bed-wetting) in persons between the ages of six and 25. Description Imipramine hydrochloride was the first tricyclic anti-depressant to be discovered. Tricyclic antidepressants act to change the balance of naturally occurring chemicals in the brain called neurotransmitters that regulate the transmission of nerve impulses between cells. Mental well- being is partially dependent on maintaining the correct balance between these brain chemicals. Imipramine is thought to act primarily by increasing the concentration of norepinephrine and serotonin (both chemicals that stimulate nerve cells) and, to a lesser extent, by blocking the action of another brain chemical, acetylcholine. Imipramine shares most of the properties of
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lecture 10 (5) - Imipramine Photo by: Sebastian Kaulitzki...

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