old474exams - Exam I: Form A. Immunology 474, Fall 2001....

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1 Exam I: Form A. Immunology 474, Fall 2001. (Chapters 1, 2, 3, and 4, Sept. 13, 2002), Name _________________________ Social security number ________________________ 37 questions (57 total points) Read all questions carefully. Only one correct answer exists for each multiple-choice question. Clearly circle correct answer. Where appropriate, fill in correct answers as indicated by question. Keep the short answers short (two to three sentences)! 1. (1 pt). Louis Pasteur cultured the organism responsible for chicken cholera and demonstrated the organism caused disease in chickens. He then discovered that certain cultures of the organism got the chickens sick, but then they recovered. Later, when he challenged these chickens with virulent cholera, they did not get sick. The term that best describes the initial inoculating culture is A. variolated. B. attentuated. C. denatured. D. immune. 2. (1 pt). Of the following, which best describes a major difference between the selective and instructional theories of immune specificity? A. The selective theory included the interaction of a receptor (or antibody) and antigen, while the instructional theory did not. B. The selective theory suggested that receptor (or antibody) specificity was determined before the receptor (or antibody) interacted with the antigen, while the instructional theory did not. C. The instructional theory led other investigators to propose the "clonal selection theory", while the selective theory did not. D. None of the above represents a major difference between the selective and instructional theory of immune specificity. 3. (1 pt). Most pathogens enter the body via the A. skin. B. gastrointestinal tract. C. respiratory tract. D. mucous membranes. E. conjunctiva.
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4. (3 pts). Describe below three defined events that lead to the influx of phagocytes into tissue following an inflammatory event and include the appropriate terms. i. ii. iii. 5. (1 pt). Fill in the blank. A number of proteins called acute phase proteins are released in response to tissue damage. One of these proteins can bind to a cell wall component of certain pathogens, which then leads directly to the activation of complement. This protein is referred to as __________________. 6. (1 pt). TRUE or FALSE. There are two major classes of major histocompatibility complex molecules, of which class II MHC molecules are found in conjunction with β 2 - microglobin. 7. (3 pts). Define the three membrane molecules indicated below by the arrows by name. 8. (2 pts). Fill in the blanks. The increased quantities of antibodies produced in a secondary immune response is due to the clonally expanded __________ _______, while an increase in the speed of tissue rejection during a secondary response is due to the clonally expanded ___________ _____________ and ____________ cells. 9. (2 pts). One type of lymphocyte has been described as MHC-I restricted. Define this
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This note was uploaded on 02/28/2012 for the course BIO 1101 taught by Professor Robinson during the Spring '09 term at University of Central Florida.

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old474exams - Exam I: Form A. Immunology 474, Fall 2001....

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