Lecture 14-15 220 BlkBd

Lecture 14-15 220 BlkBd - Potential energy in glucose is...

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Unformatted text preview: Potential energy in glucose is contained in the reduced hydrocarbon bonds. To use this energy, glucose must be oxidized to CO 2 and water. This involves Six major steps: 1) The transport of glucose into the cell using glucose transporters. 2) Glycolysis splits glucose into two pyruvate molecules. 3) Pyruvate oxidation produces acetyl coA , which is then metabolized further in: 4) 4) The citric acid (or Krebs) cycle oxidizes acetyl coA to produce ATP and reduced electron carriers NADH and FADH 2 . 5) The electron transfer chain uses NADH/ FADH 2 from the citric acid cycle and glycolysis to maintain a proton gradient across the inner mitochondrial membrane. 6) This gradient drives an enzyme, ATP synthase , to produce ATP. Releasing Energy from Glucose 1 2 3 4 5 6 Releasing Energy from Glucose The compartmentalization of these processes within the cell is critical for the efficient release of energy from glucose. They occur in different cell compartments. The movement of molecules between compartments is an important aspect of metabolism. The transport of glucose (1) between the extracellular and intracellular compartments. Glycolysis (2) requires soluble cytosolic enzymes. Pyruvate (3) moves from the cytosol to the mitochondrial matrix , where enzymes required for the citric acid cycle (4) are located. The molecules required for the electron transport chain (5) are located in the inner mitochondrial membrane , as is ATP synthase (6)....
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Lecture 14-15 220 BlkBd - Potential energy in glucose is...

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