lecture-15-handouts - 10/11/2011 Practical Bioinformatics...

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10/11/2011 1 Practical Bioinformatics for Life Scientists Week 8, Lecture 15 István Albert Bioinformatics Consulting Center Penn State Upcoming Midterm Projects Next week each handout will have a unique last sheet this will be your project You may also propose your own project A project is like a homework download, install and run the tool on a dataset of your choice: simulated, or test dataset Describe the results Some tools may spawn many domains pick a single one Holistic ” Data Analysis Put together EVERY STEP of the analysis BEFORE optimizing any of the intermediate steps Try to imagine what the end result needs to look like and work towards that goal Think of an artist drawing portrait it is a successive refinement of the entire image Origins of human genetic variation 1 A regular diploid human cell contains 46 chromosomes Ploidity=2N because 23 pairs of homologous chromosomes. One set of chromosomes inherited from each parent
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lecture-15-handouts - 10/11/2011 Practical Bioinformatics...

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