Acute and Chronic Menigitis Clinical Features Inflammation of the meninges causes fever, headache, and sometimes photophobia. There is usually nuchal rigidity though this may be minimal or absent in the very young or old and in patients with HIV infection. There is often an antecedent prodrome (fever, aching, perhaps sore throat). The CSF is almost always abnormal. The pattern of CSF abnormality (the “CSF profile”) together with the pace (rapidity of onset) of the disease, certain clinical clues (age of the patient, presence of immunosuppression, presence of cranial nerve palsies), allow the physician to develop a likely diagnosis. In the case of bacterial meningitis, the common causes differ markedly according to the age and immune status of the patient (see slide titled Risk Groups). Infection by Hemophilus influenzae, which used to be the most common cause of bacterial meningitis in young children, has nearly disappeared as a result of the vaccine.
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bacterial meningitis, lymphocytic normal glucose, lymphocytic low glucose