Bone and Joint Tex3

Bone and Joint Tex3 - 2 infants o S aureus H influenzae 3...

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Bone and Joint Text 1. Bone scan o intravenously injected radioisotope localizes to the areas of increased bone activity that occur at the site of a bone infection o very sensitive but has low specificity 2. Computed tomography (CT scan) o 3-dimensional view of affected area - visualizes bone, surrounding soft tissue and sequestra (islands of dead bone) 3. Magnetic resonance imaging (MRI) o visualizes bone and surrounding soft tissue in a 3-dimensional fashion o the appearance of the bone marrow changes due to the inflammation associated with the bone infection o test of choice for vertebral osteomyelitis
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4.3. Bone biopsy – the "Gold Standard" pathology abundant PMN's, bony necrosis, positive gram stain microbiology positive culture confirms diagnosis 5. What are the major pathogens causing Osteomyelitis? Pathogens are age specific 1. neonates o S. aureus, group B streptococci
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Unformatted text preview: 2. infants o S. aureus, H. influenzae 3. later in life o S. aureus predominates 4. adults o Usually S. aureus o "Mixed infection" (gram positive organisms, gram negative aerobes, anaerobes) - in the setting of peripheral vascular disease and/or diabetes 6. How is Osteomyelistis treated? • An individualized treatment plan is often necessary • Treatment often involves medical and surgical modalities. Treatment "failures" are frequently due to the need for more surgical treatment as opposed to more or different antibiotics. 6.1. Medical modalities • antibiotics o ex. methicillin-sensitive S. aureus osteomyelitis - optimal antibiotics are oxacillin +/- an aminoglycoside for synergy o treatment is frequently long-term (for example, 4-6 weeks) • optimization of the management of underlying conditions such as diabetes...
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This note was uploaded on 03/02/2012 for the course BSC BSC1086 taught by Professor Joystewart during the Fall '10 term at Broward College.

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Bone and Joint Tex3 - 2 infants o S aureus H influenzae 3...

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