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Unformatted text preview: Presence of foreign materials (PMN defect, adhesion of microorganisms) Diabetes (microvascular disease, poor wound healing, neuropathy) Surgery Adjacent soft tissue infection Peripheral vascular disease Sickle cell disease (devitalized bone) Congenital defects in phagocyte function 4.1. History and physical examination 1. presence of risk factors 2. fever, local pain and tenderness, swelling, decreased range of motion of a joint, erythema, warmth, drainage, sinus tracts, ulceration 4.2. Radiographic diagnosis 1. Routine radiographs ("plain films") o fairly specific but appearance of abnormalities might be delayed (up to 15 days after symptoms appear) o Cortical destruction with periosteal new bone formation Ex. 1. Salmonella osteomyelitis of the tibia, began in shaft. See cortical destruction, new bone formation and fissure in cortical bone...
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