Emerging Infectious Disease4

Emerging Infectious Disease4 - How to distinguish from...

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Emerging Infectious Diseases 9.1.2. Diagnosis culture from blood, although this occurs late in fatal disease process 9.1.3. Management antibiotics, supportive care o Ciprofloxacin o Doxycycline prophylaxis for other possibly exposed individuals o Ciprofloxacin or doxycycline for 60 days o Immunization (3 doses required at 0, 2, and 4 weeks) 9.2. Smallpox (Variola major) A unique DNA virus for which humans are its only reservoir. 9.2.1. Mode of transmission: person to person spread by air droplets/aerosols 9.2.2. Pathogenesis: Inahalation of air droplet mucosal replication and viremia dissemination to organs and skin INCUBATION PHASE (7-17 [12] DAYS) 2 ND viremia TOXEMIC PHASE rash (3-4d), high fevers, myalgias head arms + hands legs and trunk HIGHLY INFECTIOUS VIRAL SHEDDING LESIONS
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Unformatted text preview: How to distinguish from chickenpox: Smallpox lesions develop at the same pace and are uniform in appearance and deep in skin Chickenpox lesions are more superficial, develop in crops over several days and are at varying stages from vesicle to scab to crust at any given time Smallpox lesions are top heavy head, arms, legs, then trunk Chickenpox lesions most dense on the trunk 9.2.3. Treatment: isolation, supportive care 9.2.4. Prevention: vaccination before exposure or within 2 to 3 days of exposure Vaccinia live virus Complications: o Accidental infection o Generalized vaccinia o Eczema vaccinatum o Postvaccinal encephalopathy o Progressive vaccinia o Myocarditis...
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This note was uploaded on 03/02/2012 for the course BSC BSC1086 taught by Professor Joystewart during the Fall '10 term at Broward College.

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Emerging Infectious Disease4 - How to distinguish from...

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