Emerging Infectious Disease7

Emerging Infectious Disease7 - 3.4 To come into being...

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Emerging Infectious Diseases 2.4. Technology applied to industry Enterohemmorhagic E. coli in mass food processing Viral transmissions with medical use of blood and tissues Toxic shock and tampon use 2.5. Microbial adaptation Antibiotic resistance 2.6. Relaxation of public health controls Multi-drug resistant tuberculosis 3. Four definitions of Emerging Infections These pathogens reflect the four definitions of the verb “to emerge” found in Webster’s dictionary: 3.1. To become manifest: Agents of biological warfare 1. Variola virus (smallpox) 2. Bacillus anthracis (anthrax) 3.2. To rise from an obscure or inferior position or condition: Epizootic infections, transcontinental spread 1. West Nile Virus 2. (Monkeypox virus) 3.3. To rise from or as if from an enveloping fluid; to come out into view: new variant of common virus 1. Coronavirus (SARS)
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Unformatted text preview: 3.4. To come into being through evolution: evolution of resistance genes 1. Glycopeptide intermediate Staphylococcus aureus 2. Multi-drug resistant tuberculosis Do not memorize everything in this syllabus, but use it as a reference. Pay attention to the key concepts and how the emerging infections emphasize these concepts. 4. Agents of Biological Warfare 4.1. Key Concepts: Characteristics of ideal biological warfare agents 4.2. Environmental survival: spores of Anthrax viable at extremes of environmental stresses; spore size ideal for inhalation into lower respiratory tract; body temperature allows for germination and release of toxin 4.3. Widely spread before detected: smallpox long incubation period 4.4. High fatality rate: inhalational anthrax and toxin mediated cell death Viral hemorrhagic fevers...
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Emerging Infectious Disease7 - 3.4 To come into being...

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