This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: 12.1. Key Concepts: • Novel strains of MRSA infecting healthy children and adults • Strains differ from major clones of hospital acquired (HA) MRSA by: o Composition of gene cassette coding for resistance CA-MRSA strains often only resistant to ß-lactams and usually remain susceptible to s, clindamycin, and trimethroprim-sulfamethoxazole o Carriage of plasmids encoding resistance o Virulence factors (Panton-Valentine leukocidin (PVL) toxin) Likely accounts for major syndrome of skin and soft tissue infections associated with these strains • As clinician, MUST consider Methicillin Resistance even in the healthy adult with implications for appropriate choice of empiric antibiotics. 13. Evolution of Resistance Genes Vancomycin (Glycopeptide) Intermediate Staphylococcus aureus (VISA)...
View Full Document
- Fall '10
- Anatomy, Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Methicillin, patchy interstitial infiltrates, Intermediate Staphylococcus aureus