Emerging Infectious Diseases

Emerging Infectious Diseases - 12.1 Key Concepts • Novel...

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Emerging Infectious Diseases 11.4.2. Laboratory Features Lymphopenia and elevated LDH more common 11.4.3. Radiographic Features Diffuse or patchy interstitial infiltrates 11.4.4. Infection Control Measures Avoid admission to hospital of less severe cases Isolation of cases in negative pressure rooms Personal protective equipment appropriate for standard, contact AND airborne precautions mandatory (hand hygiene, gown, gloves, and N95 respirators) in addition, eye protection recommended for all healthcare workers 11.4.5. Treatment Supportive care 2 candidate vaccines based on SARS-CoV spike protein in development; intranasal vaccine promising in monkeys. role for passive immunization with intravenous immunoglobulin under investigation o For further reading see: 12. The re-challenge of Staphylococcus aureus Community acquired Methicillin Resistant S. aureus (CA-MRSA)
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Unformatted text preview: 12.1. Key Concepts: • Novel strains of MRSA infecting healthy children and adults • Strains differ from major clones of hospital acquired (HA) MRSA by: o Composition of gene cassette coding for resistance CA-MRSA strains often only resistant to ß-lactams and usually remain susceptible to s, clindamycin, and trimethroprim-sulfamethoxazole o Carriage of plasmids encoding resistance o Virulence factors (Panton-Valentine leukocidin (PVL) toxin) Likely accounts for major syndrome of skin and soft tissue infections associated with these strains • As clinician, MUST consider Methicillin Resistance even in the healthy adult with implications for appropriate choice of empiric antibiotics. 13. Evolution of Resistance Genes Vancomycin (Glycopeptide) Intermediate Staphylococcus aureus (VISA)...
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  • Fall '10
  • JoyStewart
  • Anatomy, Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Methicillin, patchy interstitial infiltrates, Intermediate Staphylococcus aureus

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