chapter18 RKW-1

chapter18 RKW-1 - Lecture Connections 18 | Amino Acid...

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Lecture Connections 18 | Amino Acid Oxidation Production of Urea © 2009 W. H. Freeman and Company
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Amino Acid Use Catabolism - for energy Use carbon backbones for replenishing metabolic cycle intermediates Protein synthesis Amino acids are not stored like carbohydrates or lipids.
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Important participants α-keto glutarate Glutamate Glutamine Aspartate Pyruvate
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Oxidation of Amino Acids is a Significant Energy-Yielding Pathway in Carnivores Not all organisms use amino acids as the source of energy About 90% of energy needs of carnivores can be met by amino acids immediately after a meal Only a small fraction of energy needs of herbivores are met by amino acids Microorganisms scavenge amino acids from their environment for fuel
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Metabolic Circumstances of Amino Acid Oxidation Amino acids undergo oxidative catabolism under three circumstances: Leftover amino acids from normal protein turnover are degraded Dietary amino acids that exceed body’s protein synthesis needs are degraded Proteins in the body are broken down to supply amino acids for catabolism when carbohydrates are in short supply (starvation, diabetes mellitus),
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Dietary Proteins are Enzymatically Hydrolyzed Pepsin cuts protein into peptides in the stomach Trypsin and chymotrypsin cut proteins and larger peptides into smaller peptides in the small intestine Aminopeptidase and carboxypeptidases A and B degrade peptides into amino acids in the small intestine
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Proteases are often Zymogens Zymogen is an inactive precursor Why prepare proteases as zymogens?
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Important in protein chemistry analysis – Toolbox of enzymes
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This note was uploaded on 03/08/2012 for the course CHEM 481 taught by Professor Wood during the Fall '10 term at BYU.

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chapter18 RKW-1 - Lecture Connections 18 | Amino Acid...

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