Unit 2 - Infection Objectives Describethesequelaeofbacterial

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    Infection
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Objectives Describe the sequelae of bacterial  infection in the body Describe the pathogenesis of viral  invasion in the body. Describe the pathogenesis of fungal  invasion in the body. Identify the clinical manifestations of  infection.
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Normal Body Flora Produce antibacterial factors that prevent  colonization by pathogenic organisms. Maintained through the integrity of the  skin, mucous membranes. Opportunistic infections: normally would  not cause disease, but will if the immune  or inflammatory systems are  compromised.
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Where do normal body flora live? Skin Nose Mouth Pharynx Colon Distal Urethra Vagina
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Infection is influenced by: Mechanism of action: direct damage to the cell. Infectivity: ability to cause infection (dependent  on the ability to multiply) Pathogenicity Virulence: potency Immunogencity Toxigenicity: production of exotoxins or  endotoxins
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Entry in the body Site of entry Skin and mucous  membranes GI, GU and  respiratory tracts Eyes Ears Route of Entry Direct contact Inhalation Ingestion Vector bite
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Characteristics of Bacteria Prokaryocytes; no distinct nucleus Aerobic or anaerobic Motile or immotile Spherical: cocci Rod-like: bacilli Spiral: spirochetes Gram negative or Gram positive
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Bacterial Invasion Growth and survival depend on the bacteria’s  ability to resist the body’s defenses and the 
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This note was uploaded on 03/07/2012 for the course 830 201 taught by Professor Leyton during the Fall '08 term at Rutgers.

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Unit 2 - Infection Objectives Describethesequelaeofbacterial

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