33941 - Janice Dorman Ph.D Director Molecular Epidemiology...

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Unformatted text preview: Janice Dorman, Ph.D. Director Molecular Epidemiology Ronald LaPorte, Ph.D. Director Disease Monitoring and Telecommunications WHO Collaborating Center GSPH The Importance of IDDM Registries Diabetes Epidemiology Team in Pittsburgh ❀ Allan Drash, M.D. ❀ Dorothy Becker, M.D. ❀ Janice Dorman, Ph.D. ❀ Lewis Kuller, M.D., Dr.PH ❀ Ronald LaPorte, Ph.D. ❀ Trevor Orchard, M.D. ❀ Thomas Songer, Ph.D. ❀ Massimo Trucco, M.D. Type I Diabetes the Epidemiologist’s Dream Disease ❚ Easy to Diagnosis ❚ Frequent but not too frequent ❚ Severe but not too severe ❚ Insulin ❚ Dynamic Epidemiology Excess Mortality 1 2 3 4 5 6 7 8 9 Type I Type II Chronic Diseases in Children 2 4 6 8 10 12 14 16 Type I CA CF MS JRA MD ❀ Identical Twins = 35% ❀ HLA Identical = 18% ❀ non asp 57 = 2% The Search for the Magic Bullet The Search for the Magic Bullet to Prevent Type I Diabetes to Prevent Type I Diabetes Prevention Prevention of Type I of Type I Toxic!!! Toxic!!! Let observations with extensive view Survey mankind from China to Peru S. Johnson, 1749 The Environmental in Preventing Diabetes Challenge Environmental Etiology of Type I diabetes ❚ Environmental agents causes disease in animals ❚ Geographic Variation ❚ Temporal Variation ❚ Migrants take on risk of new environment ❚ Environmental Factors Found to Cause Disease in the Population Prevention: Reducing the incidence of disease Last, Dictionary of Epidemiology Environmental Etiology...
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This note was uploaded on 03/08/2012 for the course PHARM 300 taught by Professor Staff during the Fall '11 term at Rutgers.

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33941 - Janice Dorman Ph.D Director Molecular Epidemiology...

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