Lect3 - Lecture 3 1 Summary of 10 steps of glycolysis...

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1 Lecture 3
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2 Summary of 10 steps of glycolysis Glucose + 2P i + 2ADP + 2NAD + -> 2pyruvate + 2ATP + 2NADH + 2H + + 2H 2 O
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3 Summary of 10 steps of glycolysis
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4 Summary of 10 steps of glycolysis
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5 Important concepts 1. Fate of pyruvate 2. Use of other sugars (fructose/galactose) 3. Regulation (key enzymes and how)
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6 Glycolysis Glucose Now what?
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7 What happens to pyruvate? When there’s no oxygen around? Muscle under exertion Note: Glycolysis generated ATP — will be used in lots of reactions by the cell to regenerate ADP NADH — Mainly used in oxidative phosphorylation (need O 2 ) to regenerate NAD +
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8 Fate of pyruvate Yeast & microorganisms (anaerobic) Muscle & microorganisms (anaerobic) Complete oxidation (aerobic)
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9 NAD + is regenerated from the metabolism of pyruvate
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10 Alcoholic Fermentation (anaerobic) Pyruvate decarboxylase is not present in animals Glucose + 2P i + 2ADP + 2H + --> 2ethanol + 2CO 2 + 2ATP + 2H 2 O Glucose + 2P i + 2ADP + 2NAD + -> 2pyruvate + 2ATP + 2NADH + 2H + + 2H 2 O v.s.
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Lect3 - Lecture 3 1 Summary of 10 steps of glycolysis...

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