Lect6 - Lecture 6 Citric Acid Cycle (II) 0 Important...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
0 Lecture 6 Citric Acid Cycle (II)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
1 Important concepts 1. Understand how citric acid cycle is regulated pyruvate -> acetyle-CoA (allosteric; phosphorylation) regulation on enzymes catalyzing citric acid cycle (allosteric) 2. Memorize glycoxylation pathway diverge from citric acid cycle after isocitrate
Background image of page 2
2 Regulation of citric acid cycle regulation of the preparation step
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
3 Regulation of citric acid cycle Allosteric regulation
Background image of page 4
4 Regulation of citric acid cycle Covalent modification of the enzyme Ca 2+ , hormones Phosphate deficiency -> inactive PDH -> glucose to lactate -> high blood levels of lactic acid -> tissue malfunction (CNS)
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
One person is taking supplement of Alanine and Leucine. It is known Alanine is broken down to pyruvate and leucine to acetyl-CoA. After taking the supplement, what is the activity of pyruvate dehydrogenase? Is it more active, less active or depends?
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 03/04/2012 for the course CHEM 114B taught by Professor Wang during the Spring '09 term at UCSD.

Page1 / 22

Lect6 - Lecture 6 Citric Acid Cycle (II) 0 Important...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online