310ExampleMidterm

310ExampleMidterm - 03-310/311 Example Midterm Exam Name: _...

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03-310/311 Example Midterm Exam Name: ________________________ Page 1 of 3 1 . (2 points each) ( a ) Find the sequence of the human Rho-GAP hematopoietic protein C1 (it is thought to play a role in regulating cytoskeletal structure). What are the first five amino acids of its sequence? ( b ) What chromosome is the gene located on? ( c ) Find the DNA sequence that encodes the protein (Hint: Find literature articles related to the protein sequence, follow the link to the article by Tribioli, and select the link to DNA sequence). What is its EMBL accession number? ( d ) Find the yeast DNA sequence with the closest homology to the human DNA sequence (Note: the homology is weak, yielding a probability of random occurrence of 0.75). What is its EMBL accession number? ( e ) What chromosome is the yeast gene located on? ( f ) Find the sequence of the yeast protein encoded by this DNA sequence. What are the five five amino acids of its sequence? ( g ) Download the 3D structure of the yeast protein. What is its PDB name? ( h ) Which of the following secondary structures is more common in the protein: a -helix, b -sheet or b -turn?
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This note was uploaded on 03/04/2012 for the course BIO 510 taught by Professor Miller during the Fall '06 term at Carnegie Mellon.

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310ExampleMidterm - 03-310/311 Example Midterm Exam Name: _...

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