Chapter 14.pe

Chapter 14.pe - Chapter 14 Antineoplastic Agents Copyright...

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Chapter 14  Antineoplastic Agents
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Neoplasm Cancer—Mechanisms of Growth Anaplasia Cancerous cells lose cellular differentiation and  organization and are unable to function normally Autonomy Cancerous cells grow without the usual homeostatic  restrictions that regulate cell growth and control This allows the cells to form a tumor
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Neoplasm Cancer—Mechanisms of Growth (cont.) Metastasis Cancer cells travel from the place of origin to develop  new tumors in other areas of the body  Angiogenesis Abnormal cells release enzymes to generate blood  vessels and supply oxygen and nutrients to the cells,  generating growth Cancerous cells rob the host cells of energy and  nutrients and block normal lymph
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The Body’s Immune System Response to  Cancerous Cells Can damage or destroy some neoplastic cells T cells recognize the abnormal cells and destroy them Antibodies form in response to parts of the abnormal  cell protein Interferons and tissue necrosis factor (TNF) play a role  in the body’s attempt to eliminate the abnormal cells
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This note was uploaded on 03/08/2012 for the course PHARM 101 taught by Professor Lyse during the Spring '12 term at HCCS.

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Chapter 14.pe - Chapter 14 Antineoplastic Agents Copyright...

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