9751 - Assault with a Chemical Weapon: Its worse out there...

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Assault with a Chemical Weapon: Its worse out there than just Bioterrorism Frank Paloucek DABAT
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Biological warfare in history ??? 6 th Cent Romans 1346 1800’s WWI 1933-45 Feces-smeared arrows Assyrians poison wells with ergot Animal cadavers into well water Plague-dead corpses catapulted into Kaffa by Tartars British donate smallpox laden blankets Germans use zoonoses against livestock Japan’s “Unit 731” kills 10,000+ Chinese with plague, anthrax, dengue, tularemia
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Lord Jeffrey Amherst, July 1763 re: Pontiac’s rebellion
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In English “You will do well to try to inoculate the Indians by means of blankets, as well as every other method that can serve to extirpate this execrable race…”
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Recent Biological Accidents or Terrorism 1978 1979 1984 1994 2000 G. Markov killed by ricin in umbrella tip Leak of military anthrax spores outside of Sverdlosk – 66+ deaths 751 people poisoned with Salmonella in Dallas OR – salad bars contaminated by local cult Aum Shinrikyu sprays botulism toxin twice and tries anthrax spore cloud 35 anthrax cases reported to FBI in US
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Anthrax History ???? 15- 1700’s 1979 1994 2001 5 th and 6 th plagues of Exodus Major livestock disease Europe Leak of military anthrax spores outside of Sverdlosk – 66+ deaths Aum Shinrikyu sprays botulism toxin twice and tries anthrax spore cloud 35 anthrax cases reported to FBI in US, ~10,000 receive 60+ days of prophylaxis
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Anthrax Bacillus anthracis (Greek for coal) Called “Black Bane” in Middle Ages Major zoonosis – id’ed in 1870 by R. Koch Id’ed as cause of Woolsorters Disease (specifically for inhalational disease ) Successful immunization in 1880, Pasteur’s vaccine developed in 1881 “Wild” prevalent in Africa, Asia and “anthrax belt” of U.S. Midwest/Great Plains
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Table 1. Potential Biological Terrorism Agents
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This note was uploaded on 03/13/2012 for the course PHARM 300 taught by Professor Staff during the Fall '11 term at Rutgers.

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9751 - Assault with a Chemical Weapon: Its worse out there...

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