BIMM 120 Lecture17.FinishMetagenomics.052611

BIMM 120 Lecture17.FinishMetagenomics.052611 - We will...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: We will discuss Paper #3 (Hehemann et al. ) at the end of class on Tuesday ...treasures in the human gut! BIMM 120 Announcements BIMM 120 Announcements In preparation of the Final Exam review on Thursday 6/2, please email me (or your TAs) to suggest topics in need of a do over Also, remember that I will be out of town Sat 6/4 Wed 6/15 forcing me to miss the live showing of the Final Exam... / Another revision to the syllabus... Please check out v6 on WebCT Homework #2 Homework #2 Identify the microbes in the flask... Identify the microbes in the flask... You are given a flask containing an enrichment of some microbes Sequence 5 clones F R (F= forward read / R= reverse read) PART I How would you characterize the composition of this flask using a genomic approach? >Clone1_fwd ATCGAGCATACGATAC.... >Clone1_rev TTCGCGAACGTAGCAC.... (you will perform a total of 10 BLAST analyses) PART II BLAST sequences against NR to identify the organisms and genes encoded on the reads PART III Perform literature searches to figure out why these organisms are in in a flask together.... What are they possibly doing & for what purpose? BIMM 120 BIMM 120 Lecture 17 Lecture 17 Finish Metagenomics Thursday May 26, 2011 ...now where were we... ...now where were we... Lecture 16 Metagenomics The power & promise of cultivation-independent DNA sequencing Metagenomics Metagenomics in action in action in situ in situ phase phase ex vivo ex vivo phase phase in in silico silico phase phase why extreme environments represent why extreme environments represent highly tractable systems for highly tractable systems for metagenomic metagenomic exploration exploration metagenomic metagenomic opportunities opportunities ; Physiology & metabolism Physiology & metabolism genetic & metabolic potential of uncultivated organisms genetic & metabolic potential of uncultivated organisms genotype : phenotype linkage genotype : phenotype linkage activity in the environment activity in the environment genes of unknown function genes of unknown function cultivating the uncultivated cultivating the uncultivated Autecological Autecological phenomena phenomena environmental adaptation environmental adaptation biogeographical biogeographical patterning patterning diversity & diversity & spatio spatio-temporal dynamics temporal dynamics environmental control of expression environmental control of expression ; modes and tempo of species evolution / selection modes and tempo of species evolution / selection Evolutionary processes Evolutionary processes species definition species definition ; Discovery Discovery novel genes, metabolisms, physiologies novel genes, metabolisms, physiologies novel diversity novel diversity ; OUTSTANDING QUESTIONS IN OUTSTANDING QUESTIONS IN MICROBIAL ECOLOGY AND EVOLUTION MICROBIAL ECOLOGY AND EVOLUTION ...the ...the metagenomic metagenomic approach......
View Full Document

Page1 / 39

BIMM 120 Lecture17.FinishMetagenomics.052611 - We will...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online