lecture32012withnotes

lecture32012withnotes - Chem 302 Course Tutor: Kai Lin Lau

Info iconThis preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Chem 302 Course Tutor: Kai Lin Lau (kai.lau@mail.mcgill.ca)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 In the laboratory (small scale; does not require high pressures): H 2 /catalyst NO 2 NH 2 NaNO 2 /HCl + N N diazonium salt (stable <5 ° C) OH N 2 + or Sn/HCl 0-5 ° C, H 2 O H 2 O, heat, Copper catalyst
Background image of page 2
3 H 2 /catalyst NO 2 NH 2 (stable <5 ° C OH N 2 or Sn/HCl 0-5 ° C, H 2 O (stable <5 C) H 2 O, heat
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4
Background image of page 4
5
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6 In the laboratory (small scale; does not require high pressures): H 2 /catalyst NO 2 NH 2 NaNO 2 /HCl + N N diazonium salt (stable <5 ° C OH N 2 + or Sn/HCl 0-5 ° C, H 2 O (stable <5 C) H 2 O, heat, Cu 2 O/CuSO 4
Background image of page 6
7 Reactions of Phenols • Ether Formation When NaHCO3 was used, only PhO- formed in significant amounts, i.e., it is the only species available to react.
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
8 • Ether Formation, cont’d
Background image of page 8
9 • Ether Formation, cont’d Order of reactivity under strongly basic conditions: RO- > PhO- >> ROH, PhOH
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
10 • Ether Formation, cont’d
Background image of page 10
11 • Ether Formation, cont’d HO NaHCO 3 CH 3 I O N Morphine Active ingredient in opium Highly addictive HO
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
12
Background image of page 12
Image of page 13
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 03/06/2012 for the course CHEM 302 taught by Professor Sleiman during the Winter '12 term at McGill.

Page1 / 42

lecture32012withnotes - Chem 302 Course Tutor: Kai Lin Lau

This preview shows document pages 1 - 13. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online