101311 Protein folding

101311 Protein folding - MEMBRANE PROTEINS H Schillers...

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MEMBRANE PROTEINS
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FLUID-MOSAIC MODEL OF MEMBRANE ORGANIZATION
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Transmembrane Peripheral PH-domains: bind PIPs MECHANISMS OF PROTEIN ASSOCIATION WITH LIPID BILAYER
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SINGLE-PASS PROTEINS
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SINGLE-PASS PROTEINS Hydropathy plot
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Hormones and nutrients SINGLE-PASS PROTEINS AS RECEPTORS
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MECHANISMS OF PROTEIN ASSOCIATION WITH LIPID BILAYER Transmembrane Peripheral PH-domains: bind PIPs
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G-PROTEIN-COUPLED (SERPENTINE) RECEPTORS Outside Inside
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BACTERIORHODOPSIN
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~20% HYDROPATHY PLOTS FOR SINGLE-PASS AND MULTI-PASS PROTEINS
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BACTERIORHODOPSIN
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MECHANISMS OF PROTEIN ASSOCIATION WITH LIPID BILAYER Transmembrane Peripheral PH-domains: bind PIPs
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β -BARRELS
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MECHANISMS OF PROTEIN ASSOCIATION WITH LIPID BILAYER Transmembrane Peripheral PH-domains: bind PIPs
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CATEGORIES OF LIPID ANCHORS: Attach protein from inside Attach protein from outside Binds N- terminus Binds C- terminus Binds in the middle COOH NH 2 NH 2 COOH Cytosol Cytosol
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N-TERMINAL MYRISTOYLATION Mutation of the myristoylation site
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This note was uploaded on 03/07/2012 for the course BIOL 212 taught by Professor Kina during the Spring '12 term at UPenn.

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101311 Protein folding - MEMBRANE PROTEINS H Schillers...

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