2011 Exam 1 Key - Purdue ID: Name: Key Biol 241 - Spring...

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Purdue ID: Name: Key Biol 241 - Spring 2011 Midterm I 2/17/2011 Question 1 (30 points) Question 2 (10 points) Question 3 (10 points) Question 4 (10 points) Question 5 (6 points) Question 6 (4 points) Question 7 (8 points) Question 8 (6 points) Question 9 (8 points) Question 10 (8 points) Total
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Biol 241, Spring 2011 Midterm Exam I Purdue ID: ___________________ 2 Question 1. Multiple-choice (30 points; 2 points each) 1) At the G1 phase of cell cycle, a chimpanzee somatic cell has 24 pairs of chromosomes. What is the expected number of chromosomes at the metaphase of meiosis I of a chimpanzee germ cell? a) 12 b) 24 c) 48 d) 96 2) Diseases such as Huntington’s can exhibit earlier onset and increased phenotypic severity in successive generations. This is caused by: a) The formation of heteroduplex at the disease-causing genes. b) The random inactivation of X-linked disease-causing genes. c) The methylation of cytosines in CG islands near the disease-causing genes. d) The expansion of tri-nucleotide repeats in the disease-causing genes. 3) With dominant epistasis, a likely ratio resulting from a dihybrid cross would be: a) 9:3:4 b) 9:7 c) 12:3:1 d) 9:3:3:1 4) Which of the following events during meiosis will generate gametes capable of producing viable progeny? a) A single crossover within the inverted region of a paracentric inversion. b) A single crossover within the inverted region of a pericentric inversion. c) Segregation of homologous chromosomes in a triploid organism. d) Alternate segregation of reciprocal translocated chromosomes.
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Biol 241, Spring 2011 Midterm Exam I Purdue ID: ___________________ 3 5) The phenomenon in which one crossover decreases the likelihood of crossovers in nearby regions is called: a) Gene conversion. b) Negative interference. c) Unequal crossover. d) Positive interference. 6) Drosophila females heterozygous for a deletion of the Notch locus exhibit “notching” defects at wing margins. Thus, Notch is an example of: a) A dominant active mutation. b) A dominant negative mutation. c) A haplo-insufficient mutation. d) A conditional mutation. 7) Avery, MacLeod, and McCarty’s experiment showed that the transforming principle is sensitive to: a) Heat. b) RNase. c) Protease. d) DNase. 8) In analyzing DNA from a species, you determine that the base composition consists of 20% adenines. What is likely the percentage of cytosines in this organism? a) 20%. b) 30% c) 40% d) 60%
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Biol 241, Spring 2011 Midterm Exam I Purdue ID: ___________________ 4 9) The following result describes the absorbance of UV light (260nm) by three nucleic acid species at increasing temperature. Assuming that they are all equal in length, what can you conclude about them from these data? a)
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This note was uploaded on 03/12/2012 for the course BIO 241 taught by Professor Henrychang during the Spring '11 term at Purdue University-West Lafayette.

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2011 Exam 1 Key - Purdue ID: Name: Key Biol 241 - Spring...

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