Lecture 11 - Bio 121 Lecture 11 Patterns of inheritance A....

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Bio 121 Lecture 11 – Patterns of inheritance A. Human Genetics a. Inconvienent for genetics a.i. Generation span 20 years a.ii. Parents produce few offspring a.iii. Some diseases can’t be detected by allele a.iv. Socially unacceptable to ask two people to perform a test cross b. Continues to advance b.i. Research interested in genes that cause human diseases b.ii. 6x10^9 base pairs in humans b.iii. About 20000 genes in humans c. Counseling c.i. Predict probability that child will have a certain disease c.ii. Dna diagnostics B. Types of Genetic Disease – .5% on nonidentical dna a. Mutation a.i. heritable change in the chemical structure in a gene a.ii. Ultimate source of genetic variation a.iii. Can have positive or negative affects b. Single gene defects (autosomal -22 pairs autosomes/1 pair sex chromosomes) c. Chromosomal disorders (downs syndrome) d. Multifactorial dieases C. Human Pedigrees – family tree where we access whats going on in the family a. Circle – female, squares – male b. Solid symble – has phenotype, open – non disease phenotype
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This note was uploaded on 03/12/2012 for the course BIO 121 taught by Professor Minchella during the Fall '10 term at Purdue University-West Lafayette.

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Lecture 11 - Bio 121 Lecture 11 Patterns of inheritance A....

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