27_Disease_ecology - Disease Ecology Today's questions: I....

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Disease Ecology Today’s questions: I. How do coevolutionary arms races work? an parasites manipulate their hosts? II. Can parasites manipulate their hosts? III. The evolution of virulence ow are human duced changes in the IV. How are human induced changes in the environment affecting infectious disease?
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I. How do coevolutionary arms races work? Malaria as a model (parasitism by 4 species of Plasmodium ) Kills people/year ckens eople/year Sickens people/year Plasmodium cells are passed from infected mosquitoes humans, and from infected humans to mosquitoes to humans, and from infected humans to mosquitoes A. Arms race I: Malaria and public health officials Use of DDT to kill mosquitoes: Chloroquine, mefloquine, other quinine derived drugs: Current emphasis: use of insecticide impregnated bed nets (mosquitoes bite at night)
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B. Arms race II: Evolutionary responses in humans Question: In areas where malaria is common, does natural selection favor individuals with resistant alleles?
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This note was uploaded on 03/08/2012 for the course BIOL 180 taught by Professor Freeman during the Fall '07 term at University of Washington.

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27_Disease_ecology - Disease Ecology Today's questions: I....

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