exam 2 - 1. A difference between vertically and...

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1. A difference between vertically and horizontally acquired mutations is that A. only vertically-acquired mutations are passed on to progeny cells B. chemical mutagens only induce vertically acquired mutations C. knockout phenotypes only result from vertically-acquired mutations D. horizontally-acquired mutations are more severe 2. Which of the following would generally be the MOST detrimental to a bacterium? A. A missense mutation upstream in a coding region B. A missense mutation downstream in a coding region C. A nonsense mutation upstream in a coding region D. A nonsense mutation downstream in a coding region 3. A base substitution that causes a silent mutation would most likely occur A. in the first base of a codon B. in the third base of a codon C. in the upstream portion of a coding region D. in the downstream portion of a coding region 4. Which of the following is NOT true of quorum sensing? A. It only occurs between different species of bacteria B. It allows bacteria to sense their population density C. It utilizes a diffusible co-inducer molecule D. It leads to changes in gene expression 5. Alkylating agents do NOT
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A. promote base substitution mutations B. cause cancer C. modify the chemical structure of DNA bases D. promote indel mutations 6. DNA intercalating agents A. cause an insertion if incorporated into the new strand during DNA replication B. are generally hydrophilic molecules C. most often generate base substitution mutations D. promote frameshift mutation 7. Which of the following is a FALSE statement about DNA methylation? A. it directs mismatch repair B. it's sensed by enzymes C. it can be found on both DNA strands immediately following replication D. it's important for the proper repair of base substitution mutations 8. Thymine dimers A. occur between thymine bases located on opposing DNA strands B. are repaired by the mismatch repair system C. can invoke the SOS response D. cannot be repaired in the dark 9. Which of the following is a FALSE statement about endonucleases? A. they are required for light repair of thymine dimers B. they include restriction enzymes
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C. they are required for mismatch repair D. they cut in the middle of DNA strands 10. 5'-bromouracil is an analog of which of the following nucleotides? A. Adenine B. Guanine C. Thymine D. Cytosine 11. The second restriction enzyme isolated from the hypothetical bacterium Universitum' washingtonia would be properly named A. Uwa RII B. Unw RII C. Uis RII D. Uni WII 12. Which of the following is a FALSE statement about DNA transformation? A. It can involve the uptake of eukaryotic DNA B. It can involve the uptake of DNA from the same or a different species of bacteria C. It involves the uptake of single-stranded DNA D. It occurs only under natural settings 13. During cloning, "cutting" and "resealing" of a DNA molecule would require A. polymerase and ligase B. exonuclease and helicase
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C. restriction endonuclease and ligase
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This note was uploaded on 03/08/2012 for the course CHEM 241 taught by Professor Unsure during the Fall '06 term at University of Washington.

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exam 2 - 1. A difference between vertically and...

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