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lecture 6 ch. 7 membranes

lecture 6 ch. 7 membranes - Ch 7 Membranes 17:47...

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Ch. 7 Membranes 17:47 Phospholipid bilayer Proteins embedded in membrane: have both hydrophobic and hydrophilic area peripheral proteins – attach to integral membrane proteins integral membrane proteins – span the membrane Fluid mosaic model (Lipids have kinks cells have a different composition outside the membrane and inside the membrane) Membrane has to have a certain fluidity at whatever temperature the organism lives in Fish in cold water: VERY fluid at 37 degrees Ratio of saturated to unsaturated More unsaturated: super fluid Addition of cholesterol Fluidity buffer At higher T, interferes with fluidity At lower T, stimulates fluidity In a common integral protein, 7 alpha helices span the membrane Loops of amino acids occur on the outside and inside of cell Loops can do anything! control metabolic activity in cell 3 loops outside: are pulled together to form binding sites for different things = receptors binding site for dopamine Inside cell:
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