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lecture 9 feb 7

lecture 9 feb 7 - 17:39 Feedback inhibition...

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17:39 Feedback inhibition Threonine (substrate) binds to enzyme 1 (threonine deaminase) intermediate A B C D isoleucine (end product) isoleucine binds to allosteric site of enzyme 1, which turns off the pathway isoleucine is used up by cell active site is available again for threonine In branched pathways, the enzyme that is subject to feedback inhibition is usually the first one committed to formation of a given product Some enzymes are regulated by several sites of feedback inhibition (up to 9!) All allosteric Ch. 9 Respiration Redox reactions Glycolysis Glucose to pyruvate Oxidative phosphorylation Acetyl—CoA to CO 2 to H 2 O Proton gradients as a form of energy Alternative pathways Regulation ATP used for all of it Steps Light harvested by plants Plants make carbon in the form of glucose, and oxygen Used by animals Prokaryotes came first not very sophisticated evolved the ability to pick up energy from light (photosynthesis)
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