Lecture 10 Feb 9

Lecture 10 Feb 9 - Electron transport chain Oxidative...

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17:31 40 multiple choice questions 6 definitions 3 short answers Glucose ATP Lots of details -__- Glycolysis – system that converts glucose pyruvate Takes 2 ATP to get system started, and 4 ATP is producer, net ATP = 2 (prokaryotes live on this...eukaryotes make more ATP) 2 pyruvate, 2 ATP, and 2 reduced cofactors Glucose (6 carbons) pyruvate (3 carbons) Oxidized further CO 2 and water lots of ATP Substrate-level phosphorylation Pyruvate (3 carbons) acetyl CoA (2 carbons) By the enzyme pyruvate dehydrogenase, transport protein into mitochondria, looks like this: S-CoA C = O CH 3 Krebs cycle – Hans Krebs “Citric acid cycle” 4-C piece attaches to acetyl CoA Requires oxaloacetate (reactant) FADH 2 . NADH – lots of energy!
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Biological systems are open and not at equilibrium
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Unformatted text preview: Electron transport chain Oxidative phosphorylation Steady state level, pool size (?) Flood the cell with carbs (glucose) Important things to know * Iron-sulfur proteins – have sulfur atoms in the active site which coordinate to put 5 bonds in the iron atom Some of them avariciously grab electrons, very strong bases Some are not so avaricious, the wimps of the iron-sulfur world (haha) affinity for electron * FMN * CoQ * FADH 2 electron transport chain *copper proteins (?) Be able to give an idea of how it works, and also the cofactors used in the electron transport chain Concentration of protons drives the formation of ATP 17:31 17:31...
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