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NAME_____________________________ STUDENT ID #___________________ SECTION #_________________________ TA_____________________________ EXAM CODE : A Academic Honesty/Integrity “I have neither given nor received aid during the administration of this exam.” ___________________________________ (Signature) ______________________________________________________________________ Biology 302 – Exam #3. November 9, 2011 True or False Questions (2 points each) 1. Dicentric refers to a chromosome in which there are two centromeres. A. TRUE B. FALSE 2. The gametes resulting from non-disjunctional segregation are euploid. A. TRUE B. FALSE 3. Female humans are mosaics of X-linked genes, thus an X inherited from their mother could be expressed in one cell lineage whereas an X inherited through their father could be expressed in another cell lineage. A. TRUE B. FALSE 4. Most restriction enzymes will cleave the DNA only of specific species, i.e., the correct restriction enzyme must be used for each species. A. TRUE B. FALSE 5. In human clinical genetics, different forms of the same disease may result from different genes and different patterns of inheritance. A. TRUE B. FALSE 6. DNA polymerase is the enzyme that adds tandem repeats to the 3' end of linear chromosomes. A. TRUE B. FALSE 7. Trisomies increase with maternal age. A. TRUE B. FALSE 8. The inversion loop formed during gene-for-gene pairing presents a problem only when a cross-over takes place. A. TRUE B. FALSE 9. Genomics is a field of study dealing with the DNA sequence, organization, function and evolution of genomes. A. TRUE
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B. FALSE 10. Eukaryotic DNA compensates for 'underwinding' by producing positive supercoils. A. TRUE B. FALSE 11. Gene dosage is upset in a euploid. A. TRUE B. FALSE 12. The C-value paradox refers to the observation that genome size correlates with organismal complexity. A. TRUE B. FALSE 13. A plasmid is a DNA molecule that is not capable of replication independent of the bacterial chromosome. A. TRUE B. FALSE 14. Single-gene traits offer excellent case studies for understanding novel gene function or providing insight into human evolution, and they are very common. A. TRUE B. FALSE 15. The gametes resulting from disjunctional segregation are aneuploid. A. TRUE B. FALSE 16. In recombinant DNA, DNA fragments are isolated, inserted into suitable vector molecules, and introduced into bacteria or yeast cells where they are replicated. A. TRUE B. FALSE 17. DNA termini without overhangs produced by endonuclease digestion are called sticky ends. A. TRUE B. FALSE 18. A transposable element is a minimal genome which contains a set of genes and regulatory sequences that enables it to produce copies of itself, change its genomic location, or both. A. TRUE
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