BIS 104 PQ 28 - Suppose that the length of the axon is 600...

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BIS 104 PQ 28 28. It has been determined that a cargo vesicle can be moved along a MT toward the “plus” end at a rate of ~3 micrometers per second (3 um / sec). And, each individual kinesin motor protein step covers ~8 nanometers (nm). a. How many steps can a kinesin molecule make in one minute? b. A neuron has to transport acetylcholine packaged in a vesicles from the near the nucleus, down the axon, to the cell tip for release at a synapse.
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Unformatted text preview: Suppose that the length of the axon is 600 micrometers (um). Assuming the kinesin motor shows processive movement and doesn’t stumble and fall off the MT, how many minutes will it take to deliver the cargo vesicle? c. What three cellular parameters might influence the rate of cargo movement? d. After kinesin motor proteins and dyneins transport their cargos to one end of a MT, how do you suppose these motor proteins get back to their origin?...
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This note was uploaded on 03/16/2012 for the course BIOLOGY BIS104 taught by Professor Bejjamin during the Fall '10 term at UC Davis.

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