This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: Lambert-Eaton myastenic syndrome o Problem controlling muscles, autoimmune Ca2+ destroyed • Latroxin =massive release w/o calcium, from black widow spider, bypasses need for calcium • Botulism o Bacterium Clostridium botulinum o Toxin interferes with muscle contraction/can cause paralysis o Small doses used in BOTOX • Naxos disease o 2 causative genes coding for proteins plakoglobin and desmoplakin o woolly hair, progressive heart disease • Yersinia (food/water borne) o cell adhesion with cadherins, targets cell surface proteins • Listeria (raw meats) o 25% lethal can cause bacterial meningitis o hijack normal cell adhesion of gut • Ehlers-Danlos Syndrome o Collagen Defect o Can stretch skin and bend joints abnormally • Marfan’s Syndrome o Defect in Elastin o Able to bend joints abnormally....
View Full Document
- Spring '12
- blood glucose, blood glucose level, CELL MOLEC EXAM, release w/o calcium, Lambert-Eaton myastenic syndrome