04BIS1012012RecombinLect4b

5 is large and gives a probability p of 0005 or 05

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Unformatted text preview: ypothesis that the B and C loci are unlinked. Conversely, we must consider that B and C are linked. The 2 test does not prove that B and C are linked -- only that our hypothesis does not fit the data well. 2 is a measure of goodness of fit. March 19, 2012 BIS101001, Spring 2012--Genes and Gene Expression, R.L. Rodriguez 2012 53 Chi Square (2) Table Critical Values of the 2 Distribution Hypotheses that deviations are due to chance alone are rejected for probabilities less than 5% or 0.05 March 19, 2012 BIS101001, Spring 2012--Genes and Gene Expression, R.L. Rodriguez 2012 54 Summary The frequency of recombination between non-sister chromatids during prophase 1 of meiosis can be used to construct genetic maps. The farther two loci are from each other, the greater the likelihood that multiple crossovers will go undetected. Undetected crossovers reduce the accuracy of genetic maps. Genetic maps can be corrected using the mapping function. The Chi-square formula can be used to test the "fitness" of progeny data to the working hypothesi...
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