{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}


Genetic distance the distance between gene loci on a

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ce: The distance between gene loci on a chromosome can be measured in terms of the recombination frequency (RF), produced by crossing over between two loci during meiosis. Roughly, 1% recombination equals 1 map unit (m.u.) for short distances (e.g., 1 to 15% RF). Gene order and the 3 factor cross (trihybrid cross) : Interlocus map distances based on recombination measurements are roughly additive and can be used to determine gene order. Interference: One crossover can influence the occurrence of a second crossover in an adjacent region. Interference distorts map distances. Mapping function: For recombination frequencies (RF) larger than 15%, the 1 to 1 relationship between RF and m.u. breaks down. For example, an RF of 27.5% actually equals 40 m.u. March 19, 2012 BIS101001, Spring 2012--Genes and Gene Expression, R.L. Rodriguez 2012 3 Linkage Genes are linked to other genes. What does this mean for Mendelian inheritance and how can linkage be used to understand gene and chromosome structure? March 19, 2012 BIS10...
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online