04BIS1012012RecombinLect4b

This approach can be performed without rare double

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Unformatted text preview: ossovers (data from Bridges and Olbrycht, 1925). Three recessive X-linked genes in Drosophilia: sc=scute; ec=echinus; cv=crossveinless F1 + + ec X sc cv ec tester 29 sc cv + March 19, 2012 BIS101001, Spring 2012--Genes and Gene Expression, R.L. Rodriguez 2012 3 Factor Test Cross without Double Crossovers F1 + + ec X sc cv ec sc cv + tester Progeny Phenotypes + + ec 810 sc cv + 828 + cv + 88 sc + ec 62 + cv ec 89 sc + + 103 1980 1. 2. March 19, 2012 Parental Phenotype 3 2 + sc 1 + cv ec + Compare recombination between 3 pairs of loci (1, 2 and 3) sc-cv 88+62+89+103 = 342/1980 X 100 = 17.3% cv-ec 89+103 = 192/1980 X 100 = 9.7% sc-ec 88+62 = 150/1980 X 100 = 7.6% BIS101001, Spring 2012--Genes and Gene Expression, R.L. Rodriguez 2012 30 3. 3 Factor Test Cross without Double Crossovers 1. 2. 3. sc-cv 88+62+89+103 = 342/1980 X 100 = 17.3% cv-ec 89+103 = 192/1980 X 100 = 9.7% sc-ec 88+62 = 150/1980 X 100 = 7.6% Begin mapping with closest loci 7.6 ec sc By adding the third locus, 2 alternative maps emerge 7.6 9.7 Correct or c...
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