9-9-10

9-9-10 - HemophiliaX(h = X w allele that does NOT code for...

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Unformatted text preview: 9-9-10HemophiliaX(h) = X w/ allele that does NOT code for clottingX = X w/ “clotting” alleleWho’s is more likely to have X-inked recessive diseases? MalesIf a “bad” allele on X, nothing on Y to compensateB. Chromosomal Abnormalities-Ex. Down’s syndrome, fragile X (X0, XXX, XXY, XYY)-Environment can help them grow up semi-independent-Down’s syndrome – Three 21stautosomesoMeiosis- chromosomes don’t separate properlyoDuring crossing over, 3 goes to 1 sister cell, and 1 goes to the otheroEnd count – 2 – 1 – 1 – 0 in each cell.oFragile X: CGG repeatsC. Polygenic Traits: Due to multiple genes-Most psychological and some physical traits (skin color)IV. Additional reason why some deadly genes don’t fade away-Heterozygotes may be protected against other disease.oEx. Sickle cell anemiaAutosomal recessive S= normal bloods= sickle cellsSS = normal bloodss= sickle cells - anemia and painSs = mild anemia because S not fully dominant over sAdvantages of Ss? Protects against malariaAdvantages of Ss?...
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This note was uploaded on 03/20/2012 for the course DEP 3103 taught by Professor Lane during the Fall '08 term at FSU.

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9-9-10 - HemophiliaX(h = X w allele that does NOT code for...

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