Chapter 9 (2)

Chapter 9 (2) - Chapter 9 10/07/09 -Avery, MacLeon, and...

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Chapter 9 10/07/09 -Avery, MacLeon, and McCarty What is the transforming material? o Cell extracts treated with protein, carbohydrate, and RNA digesting enzymes could still transform bacteria o Cell extracts treated with DNA-digesting enzymes lost their transforming ability o Concluded that DNA transforms bacteria -What is the Structure of DNA? Nucleotide Bases in DNA o Each nucleotide has a phosphate, deoxyribose sugar, and N-containing base (page 151) A nucleotide strand o Nucleotide strands are always assembled from the P end to the S end o Covalent bond b/n the sugar of one nucleotide and the phosphate of a second The Watson-Crick model of DNA structure (fig. 9-3) o DNA is a double helix of 2 nucleotide strands o Complementary base pairs hold the 2 nucleotide strands together o Complementary stands run in opposite directions Base Pairing in DNA o Chargaff’s rule A=T C=G o Adenine and Thymine always form pairs 2 hydrogen bonds o Cytosine and Guanine always form pairs
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Chapter 9 (2) - Chapter 9 10/07/09 -Avery, MacLeon, and...

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