Chapter 15 (2)

Chapter 15(2) - /4/09 Using knowledge of evolution to fight disease Diagnosed HIV positive in 1991 Usual time b/n HIV diag death from AIDS 8-10

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Chapter 15 11/4/09 Using knowledge of evolution to fight disease Diagnosed HIV positive in 1991 How has Magic managed to stay healthy? Hint: think about natural selection Population Genetics and Evolution Gene Pool o Total of all alleles of all genes in a population o If we are only examining 1 gene, then total of all alleles of that gene in a population Genotype frequency o Relative proportion of genotypes in a population Allele frequency o Relative proportion of each allele of a gene in a population Allele frequency o Dominant allele (A) = p o Recessive allele (a) = q o p + q = 1 Genotype frequency o Homozygous dominant (AA) = p 2 o Heterozygous (Aa) = 2pq- o Homozygous recessive (aa) = q 2 o p 2 + 2pq + q 2 = 1 Hardy-Weinberg Equilibrium Equilibrium = no change over time Hypothetical population that doesn’t evolve over time Assumptions o No mutation
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This note was uploaded on 03/20/2012 for the course BIOL 1001 taught by Professor Minor during the Fall '08 term at LSU.

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Chapter 15(2) - /4/09 Using knowledge of evolution to fight disease Diagnosed HIV positive in 1991 Usual time b/n HIV diag death from AIDS 8-10

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