Thirteen - Signal Transduction

Thirteen - Signal Transduction - 3/5 and 3/7/12 MCB 2000...

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Unformatted text preview: 3/5 and 3/7/12 MCB 2000 Lecture 16 Signal Transduction How do cells sense and process information? Molecular Circuits 3/5 and 3/7/12 MCB 2000 Lecture 16 Signal Transduction: An Adaptive Response Signals Receptors cellular location Signal amplification G proteins Second messengers Activation of kinases and phosphatases Cellular response Signal Termination 3/5 and 3/7/12 MCB 2000 Lecture 16 Two Outcomes of Signal Transduction Pathways Change the activity of an enzyme or group of enzymes Increase or decrease gene expression 3/5 and 3/7/12 MCB 2000 Lecture 16 What are the signals? hormones and growth factors neurotransmitters smells taste sensations light extracellular matrix 3/5 and 3/7/12 MCB 2000 Lecture 16 General Characteristics of Signal Transduction Pathways Specificity: Receptors Plasma membrane Polypeptide hormones; other molecules which are not permeable to the membrane Cytoplasmic Steroid hormones 3/5 and 3/7/12 MCB 2000 Lecture 16 Very Important General Characteristics of Signal Transduction Pathways...
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Thirteen - Signal Transduction - 3/5 and 3/7/12 MCB 2000...

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